Vitamin D status is closely associated with measures of physical function and frailty in acutely unwell older patients, according to new research being presented at the Society for Endocrinology’s annual conference in Scotland this week.
As part of the study, researchers examined data on 1,332 patients aged 65 years and older who were admitted acutely to hospital. Information was collected on physical function and frailty markers as well as clinical diagnosis, management and outcomes. Vitamin D status was assessed in a substudy of 766 patients.
Median serum 25OH-vitamin D was 31 nmol/L. The researchers found that patients in the lowest quartile for vitamin D had significantly longer length of stay compared to those in the highest quartile (median 34 days vs. 10 days; P<.05 they also had abbreviated mental test scores higher waterlow a trend towards falls and lower manchester mobility scores. total of per cent patients died in the lowest vitamin d quartile versus highest quartile.>
The authors said prospective supplementation studies are needed in this patient group to establish causality, investigate mechanisms, and assess the impact on rehabilitation potential and clinical outcomes.