Study identifies critical period for cardiovascular complications following sepsis


  • Mary Corcoran
  • Univadis Medical News
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Patients recovering from sepsis have a markedly elevated risk of myocardial infarction (MI) or stroke in the first four weeks after discharge from hospital, and may require closer monitoring and pharmacologic prevention during this period, suggests new research. 

For the study, researchers examined data on more than 1 million patients from the Longitudinal Health Insurance Database in Taiwan, of whom 42,316 patients had sepsis. The risk of MI and stroke following sepsis was compared with a matched population and hospital control cohort.

They found patients recovering from sepsis had a markedly elevated risk of MI or stroke in the first four weeks after discharge from hospital, with the highest risk in the first week after discharge. Younger patients had a higher risk of MI and stroke than older patients. 

This latest study, published in the Canadian Medical Association Journal, extends the findings of a Danish study that reported similar trends. “Based on our study (Han Chinese) and the study in Denmark (European) that reported similar findings for two different ethnic groups, it is likely that these results are generalisable to different populations," the authors said.