- ST-segment elevation with COVID-19 presents in a variable way, with nonobstructive disease highly prevalent, elevated d-dimer, and a poor prognosis.
Why this matters
- ST-segment elevation with COVID-19 has been reported in a number of countries.
- These authors note that the cause of myocardial injury in COVID-19 has yet to be established.
- Median age, 63 years; 83% men.
- 10 had it at presentation; 8 developed it during hospitalization.
- 14 had focal ST-segment elevation.
- 5 had normal left ventricular ejection fraction (LVEF), 8 had reduced LVEF, 1 did not undergo echo.
- 4 had diffuse ST-segment elevation, 3 with normal LVEF, 1 with LVEF 10%.
- 9 patients had coronary angiography; 6 of these had obstructive disease, 5 of whom had percutaneous coronary intervention.
- 18/18 had elevated d-dimer; the 8 with myocardial infarction had higher d-dimer and median peak troponin.
- 13/18 died in-hospital.
- Case series of 18 patients at 6 hospitals.
- Funding: None disclosed.
- Case series with small numbers.
- Patients varied in comorbidities, presentation, lung status, treatment regimen.