Significant increase in fracture risk after gastric bypass surgery


  • Mary Corcoran
  • Univadis Medical News
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Findings from a new study suggest that the risk of fracture could increase by around 30 per cent after gastric bypass surgery. 

Researchers analysed data from Swedish national databases on 38,971 obese patients undergoing gastric bypass surgery, of which 7,758 patients had diabetes and 31,213 did not. Patients were compared with obese controls with (n=7,758) and without (n=31,213) diabetes. 

During a median follow up of 3.1 years, the authors found gastric bypass surgery was associated with an approximately 32 per cent increased risk of any fracture in patients without diabetes and an increased risk of around 26 per cent in patients with diabetes. The fracture risk appeared to increase with time. The risk increase applied to fractures in general, with the exception of the lower leg, with the authors identifying a significantly reduced risk of lower leg fracture after surgery. They noted that larger weight loss or poor calcium and vitamin D supplementation after surgery were not associated with an increased fracture risk. 

The authors also found the risk of fall injury increased after gastric bypass, which they said could contribute to the increased fracture risk.  

The findings are published in the Journal of Bone and Mineral Research