Reduction in paediatric asthma cases linked to reduced antibiotic use


  • Heather Mason
  • Univadis Medical News
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An unexpected benefit of prudent antibiotic use during infancy is a reduction in the incidence of asthma, according to a study reported in Lancet Respiratory Medicine.

Antibiotic prescribing data were obtained from a Canadian population-based database. Aggregate data on annual asthma incidence and prevalence taken from a ministry of health dashboard revealed a relative decrease in asthma incidence of 26 per cent between 2000 and 2014.

The association of systemic antibiotic use (at age

Results found a decrease in antibiotic use in infancy (age

Gut microbiota samples collected from infants at three and 12 months of age were found to be a significant mediator between outpatient antibiotic exposure in the first year of life and asthma diagnosis at age five years.