An unexpected benefit of prudent antibiotic use during infancy is a reduction in the incidence of asthma, according to a study reported in Lancet Respiratory Medicine.
Antibiotic prescribing data were obtained from a Canadian population-based database. Aggregate data on annual asthma incidence and prevalence taken from a ministry of health dashboard revealed a relative decrease in asthma incidence of 26 per cent between 2000 and 2014.
The association of systemic antibiotic use (at age
Results found a decrease in antibiotic use in infancy (age
Gut microbiota samples collected from infants at three and 12 months of age were found to be a significant mediator between outpatient antibiotic exposure in the first year of life and asthma diagnosis at age five years.