Following the ‘Portfolio dietary pattern’ could lead to clinically meaningful improvements in LDL cholesterol (LDL-C) and other established cardiometabolic risk factors along with estimated 10-year coronary heart disease (CHD) risk. That is according to a new review and meta-analysis of data on the subject published in Progress in Cardiovascular Diseases.
The diet has four main components namely; 45 g/day nuts, 50 g/day plant protein, 20 g/day viscous fibre, and 2 g/day plant sterols.
Researchers examined data from seven trials including 439 participants with hyperlipidaemia in which the Portfolio dietary pattern was given on a background of a National Cholesterol Education Program (NCEP) Step II diet.
They found the combination of a portfolio dietary pattern and NCEP Step II diet reduced LDL-C by around 17 per cent. The diet also lowered non-HDL cholesterol, apolipoprotein B, total cholesterol, triglycerides, systolic and diastolic blood pressure, and C-reactive protein compared with an NCEP Step 2 diet alone. Estimated 10-year risk of CHD was reduced by 13 per cent.
The authors said the findings suggest the Portfolio diet may be a useful add-on to statin therapy or statin plus ezetimibe therapy to help achieve lipid targets.