Optimal blood pressure for reducing dementia risk in patients with atrial fibrillation


  • Mary Corcoran
  • Univadis Medical News
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Dementia risk in mid-life patients with atrial fibrillation (AF) can be reduced by controlling high blood pressure to

Researchers examined associations between systolic blood pressure (SBP) and incidence of dementia among 196,388 patients with AF aged 50 years and older, focusing on the effects of age. The risk of dementia according to SBP levels was assessed in age groups of 50-­59 years, 60-­69 years, 70-79 years and 80 years or older. 

After a median follow-up of 4.3 years, the researchers found SBP ≥130 mmHg at 50-59 years and ≥140 mmHg at 60-69 years significantly increased dementia risk, with SBP 120-129 mmHg as reference. Sub-analysis among those with a follow-up BP measurement 1.8 years after baseline BP measurement revealed that lowering SBP to

The study found, however, that lowering BP in patients above 70 years may not have as big of an impact on dementia risk.