New recommendations for low-risk kidney transplant patients


  • Dawn O'Shea
  • Univadis Medical News
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The European Renal Association - European Dialysis and Transplant Association (ERA-EDTA) has published new recommendations that set out a reduced list of required investigations for kidney transplantation in low-risk patients.

Existing guidelines on evaluation for kidney transplantation target the entire spectrum of patients with end-stage renal disease. The ERA-EDTA Developing Education Science and Care for Renal Transplantation in European States (DESCARTES) Working Group has proposed that in a subset of relatively young patients (

The ERA-EDTA now recommends the following restricted list of diagnostic tests for low-risk patients:

  • History and physical examination
  • Full blood count
  • Liver enzymes
  • International normalised ratio/activated partial thromboplastin time
  • Screen for hepatitis B and C virus, HIV, cytomegalovirus, Epstein-Barr virus, varicella-zoster and syphilis.
  • Parathyroid hormone assay
  • Urine culture 
  • Chest X-ray
  • Electrocardiogram
  • Kidney ultrasound
  • Cancer screening according to national guidelines
  • Regular dentist visit
  • Screening for latent mycobacteria infection
  • Review native kidney biopsy
  • Genetic testing

The new recommendations are based on the results of an opinion survey of 80 transplant professionals from 11 European states. There was some disagreement regarding the small number of diagnostic procedures, which was related to geographical and professional background.