International guidelines for the assessment and management of polycystic ovary syndrome (PCOS) have been developed by the International PCOS Network in partnership with the American Society for Reproductive Medicine (ASRM) and the European Society of Human Reproduction and Embryology (ESHRE).
The organisations say the diagnosis and treatment of PCOS remain controversial. They point to challenges in defining individual components within diagnostic criteria, a range of phenotypes, ethnic differences and variation in clinical features across the life course. These factors contribute to variation in diagnosis and care across geographical regions and health professional groups, which culminates in delayed diagnosis and dissatisfaction with care, they say.
“In this context, there was a compelling need for development and translation of an international evidence-based guideline for assessment and management of PCOS, addressing psychological, metabolic and reproductive features of PCOS, promoting consistent evidence-based care and guiding and encouraging research in PCOS,” the guideline document states.
The guideline is the culmination of the work of over 3,000 health professionals and consumers internationally. Thirty-seven organisations across 71 countries collaborated, with 23 face-to-face international meetings over 15 months. Sixty prioritised clinical questions were identified, generating 166 recommendations and practice points.
The guideline is available here.