- Post-traumatic stress disorder (PTSD), anxiety, and depression are common for up to 9 months after early pregnancy loss.
Why this matters
- More than 250,000 miscarriages and 10,000 ectopic pregnancies occur annually in the UK.
- The psychological consequences of miscarriage and ectopic pregnancy are not well characterized.
- Prevalence of morbidity at 1 month after early pregnancy loss:
- PTSD, 29%.
- Moderate/severe anxiety, 24%.
- aOR, 2.14 (95% CI, 1.14-4.36).
- Moderate/severe depression, 11%.
- aOR, 3.88 (95% CI, 1.27-19.2).
- The prevalence of each disorder declined over time:
- PTSD: 21% at 3 months vs 18% at 9 months.
- Moderate /severe anxiety: 23% vs 17%.
- Moderate/severe depression: 8% vs 6%.
- Evolution of morbidity was no different between ectopic pregnancy and miscarriage (PTSD, P=.43; anxiety, P=.14; depression, P=.07).
- The prospective multicenter Psychological Impact of Early Pregnancy Events cohort study.
- Longitudinal assessment of psychological morbidity in women after early pregnancy loss (n=1201) compared with controls (n=195).
- Participants were recruited from 3 early pregnancy assessment units in London.
- Participants were asked to complete a survey sent by email.
- The Hospital Anxiety and Depression Scale and the Post-traumatic Stress Diagnostic Scale used to assess morbidity.
- Funding: Individual author support only.
- High drop-out rate.