Increasing vitamin K intake may help not hinder patients on warfarin


  • Mary Corcoran
  • Univadis Medical News
El acceso al contenido completo es sólo para profesionales sanitarios registrados. El acceso al contenido completo es sólo para profesionales sanitarios registrados.

New research suggests that increasing vitamin K intake may help rather than hinder patients taking warfarin. 

As part of a new trial, researchers investigated whether increasing dietary vitamin K intake by ≥150 µg/day improves anti-coagulation stability of warfarin-treated patients with a history of international normalised ratio (INR) instability. Patients were randomised to an intervention group (VK) and received dietary counselling to increase their vitamin K intake by ≥150 µg/day through specific food choices, recipes and cooking strategies, while patients from the control (C) group received general dietary information of similar intensity. 

A total of 49 participants completed the study. After six months, 50 per cent of those counselled to increase their vitamin K intake were maintaining stable anti-coagulation levels, compared with around 20 per cent of those who received the general nutritional counselling. 

"I think all warfarin-treated patients would benefit from increasing their daily vitamin K intake,” said lead study author Guylaine Ferland. "That said, given the direct interaction between dietary vitamin K and the action of the drug, it is important that (higher) daily vitamin K intakes be as consistent as possible."

Ferland added: “Our hope is that healthcare professionals will stop advising warfarin-treated patients to avoid green vegetables.”