Higher risk of cardiometabolic disorder in patients with Tourette Syndrome


  • Mary Corcoran
  • Univadis Medical News
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Findings from a new study have led researchers to call for careful monitoring of cardiometabolic health in patients with Tourette syndrome (TS) or chronic tic disorder (CTD). The study, published in JAMA Neurology, found that TS and CTD were linked to a higher risk of metabolic and cardiovascular disorders compared with the general population and sibling controls. 

The longitudinal population-based cohort study included 14,045,026 people living in Sweden between 1 January 1973 and 31 December 2013. Of these 7,804 individuals had a registered diagnosis of TS or CTD in specialist care. 

The study found individuals with TS or CTD had nearly double the risk of any cardiometabolic disorders compared with the general population (hazard ratio adjusted by sex and birth year [aHR] 1.99; 95% CI 1.90-2.09) and a higher risk than sibling controls (aHR for any disorder 1.37; 95% CI 1.24-1.51). 

Exclusion of individuals with comorbid attention-deficit/hyperactivity disorder reduced but did not eliminate the risks.  

“The results highlight the importance of carefully monitoring cardiometabolic health in patients with TS or CTD across the lifespan, particularly in those with comorbid attention-deficit/hyperactivity disorder,” the authors said.