ENDO 2019: impact of weight loss on migraine in obese patients


  • Mary Corcoran
  • Univadis Medical News
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Weight loss through either bariatric surgery or behavioural intervention could help to reduce migraine in patients with obesity, according to new research presented at the Endocrine Society’s annual meeting earlier this week. 

In a meta-analysis of 10 studies that met the researchers' inclusion criteria and included 473 patients, the authors found that weight loss was linked with significant reductions in headache frequency, pain intensity and disability (all P<.0001 well as attack duration improvement in migraine was not correlated either to the degree of obesity at baseline or weight reduction. authors also found effect on similar when reduction obtained with bariatric surgery behavioural intervention and comparable adult paediatric populations.>

Although the authors said the mechanisms linking obesity, weight loss and migraine headache remain unclear, they may include alterations in chronic inflammation, adipocytokines, obesity co-morbidities and behavioural and psychological risk factors.

The study is a collaboration between the University of Padova, Italy, and The Miriam Hospital/Brown Alpert Medical School in Providence, Rhode Island in the United States.