- Patients with depressive disorders were more likely to develop benign paroxysmal positional vertigo (BPPV) than those without depressive disorders.
- Risk was exacerbated in the presence of hyperthyroidism and systemic lupus erythematosus.
Why this matters
- Prior studies on the association between BPPV and depression yielded conflicting results.
- Study of 10,297 patients with depressive disorders and 41,188 patients without depressive disorders (control group).
- Funding: National Science Council, Taiwan; Taipei Veterans General Hospital.
- Median follow-up duration was 7.19 years for patients with depressive disorders and 7.22 years for those without.
- 44 patients were diagnosed with BPPV in the depressive disorders group vs 99 patients in the control group (0.59 vs 0.33 per 1000 person-years; incidence rate ratio, 1.79; P=.002).
- Risk for BPPV was significantly higher in patients with depressive disorders (HR, 1.55; P=.019).
- Hyperthyroidism (HR, 3.75; P=.001) and systemic lupus erythematosus (HR, 3.47; P=.038) showed significant association with risk for BPPV in patients with depressive disorders.
- Retrospective design.
- Lack of detailed information regarding medications administered for BPPV, tobacco use, alcohol consumption, head position in bed, and family history.
Coauthored with Antara Ghosh, PhD