- In a retrospective analysis of patients with Crohn’s disease (CD) undergoing laparoscopic surgery, preoperative exclusive enteral nutrition (EEN) was associated with fewer postoperative complications.
Why this matters
- About 80% of patients with CD require bowel surgery.
- This population is frequently malnourished, and malnutrition has been linked to postoperative morbidity and mortality.
- Few data exist on EEN before laparoscopic surgery.
- 29.2% (35) of patients had complications; 21 complications were major.
- EEN vs non-EEN:
- Complications: 17.8% vs 36.0% (P=.033).
- Surgical-site infections: 8.9% vs 24.0% (P=.038).
- Endoscopic recurrence at 6 months: 11.9% vs 28.4% (P=.044).
- No between-group differences in clinical recurrence.
- EEN predicted (lower risk for) endoscopic recurrence: OR, 0.328 (95% CI, 0.113-0.949; P=.040).
- Retrospective analysis of prospectively collected data at Sir Run Run Shaw Hospital, Hangzhou, China (n=120).
- Participants underwent elective laparoscopic bowel resection for CD.
- All were advised to use EEN via nasogastric tube for 4 weeks before surgery; 45 did so.
- Those who did not worked with nutritionists and received similar calorie and protein levels.
- Outcome: postoperative complications; recurrence.
- Funding: National Natural Science Foundation of China, Zhejiang Natural Science Foundation.
- Small, nonrandomized, single-center study; risk for residual confounding.
- Non-EEN group several years older, on average.