Concussion is associated with increased risk of follow-up diagnoses of attention-deficit hyperactivity disorder (ADHD), mood and anxiety disorders (MADs), dementia and Parkinson’s disease, according to a study published in Family Medicine and Community Health.
The retrospective population-based cohort study used administrative health data for the Province of Manitoba in Canada between 1990-1991 and 2014-2015. All concussed subjects were matched with healthy controls (3:1) ratio based on age, sex and geographical location.
A total of 47,483 individuals were diagnosed with a concussion, of whom 28,021 men (mean age 18 years) and 19,462 women (mean age 30 years) were included in the concussion group. All concussed subjects were matched with healthy controls (3:1) ratio based on age, sex and geographical location. A total of 81,871 men (mean 25 years) and 57,159 women (mean 30 years) were included in the matched control group.
Concussion was associated with an increased risk of diagnosis for all four conditions of interest later in life. Adjusted hazard ratios (aHR) were 1.39; 95% CI 1.32-1.46, P<.001 for adhd ci p mads dementia and parkinson disease.>