Current guidelines suggest cholecystectomy during the third trimester of pregnancy is safe for both the woman and the foetus. However, no population-based study has examined this issue. A new study has compared the results of cholecystectomy during the third trimester of pregnancy with outcomes in women operated on in the early postpartum period and has found that maternal delivery and procedure-related outcomes are worse when cholecystectomy is performed during the third trimester.
The study compared outcomes in 403 women undergoing cholecystectomy during the third trimester with 17,490 undergoing the procedure in the three months postpartum.
It found that cholecystectomy during pregnancy was more likely to require hospitalisation (85% vs 63%; P<.001 composite maternal outcomes ratio p including preterm delivery as well the length of hospital stay days and readmissions were also significantly increased. authors point out that increased may be explained by need for additional foetal surveillance more conservative approaches healthcare providers surrounding pregnant patients.>
Based on the findings, the authors advise that, whenever possible, cholecystectomy for benign biliary disease should be delayed until the postpartum period.