Birth of first infant through maternal spindle transfer


  • Mary Corcoran
  • Univadis Medical News
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The Institute of Life IVF Center in Greece and Embryοtools in Spain are reporting the birth of the first infant through the implementation of a 'pioneering' maternal spindle transfer method. 

The infant, weighing 2.960 grams, was born on 9 April to a 32-year-old Greek woman with a history of multiple in-vitro fertilization (IVF) failures and poor oocyte quality.

The method, which was developed after five years of basic research at Embryotools in Spain and 2.5 years of clinical validation at the Institute of Life’s laboratory in Greece, was developed to address fertility issues associated with multiple IVF failures caused by cytoplasmic dysfunction of the oocytes or rare mitochondrial genetic diseases. It involves mitochondrial replacement in human oocytes, fully preserving the genetic material of the woman who wants to reproduce. 

Embryotools co-founder, Dr Nuno Costa-Borges said the completely successful and safe implementation of the method for the first time in medical history represents 'a revolution' in assisted reproduction. 

“We are very proud to announce an international innovation in assisted reproduction, and we are now in a position to make it possible for women with multiple IVF failures or rare mitochondrial genetic diseases to have a healthy child,” added Institute of Life President, Dr Panagiotis Psathas.