- Admission hyperglycemia, not only diabetes status, predicts in-hospital and 1‐year death in patients with acute heart failure (AHF).
- Consider careful monitoring and intensive heart failure therapy in AHF patients with admission hyperglycemia, regardless of diabetes status.
Why this matters
- Blood glucose levels can be transiently elevated because of stress response to acute illness.
- Few data are available on the effect of admission hyperglycemia on clinical outcomes in AHF.
- Among AHF patients in nationwide registry, 5541 were divided into 4 groups based on presence/absence of admission hyperglycemia (>200 mg/dL) and diabetes.
- Funding: Research of Korea Centers for Disease Control and Prevention.
- Of 2125 with diabetes (38.6%), diabetes was known in 92.3% and newly diagnosed in 7.7%.
- Admission hyperglycemia was found in 37.6% with diabetes and 7.3% without.
- Admission hyperglycemia significantly predicted death both in hospital (7.6% with vs 4.2% without; P<.001 and at year with vs without>
- Diabetes predicted death at 1 year (24.8% with vs 20.5% without; P<.001 but not in hospital.>
- In multivariate analysis, admission hyperglycemia independently predicted in-hospital death (OR, 1.84; P=.017 for diabetes and OR, 2.26; P<.001 nondiabetes and death p=".030)" regardless of diabetes status.>
- Missing registry data.
- No HbA1c rule-out criteria for suspected diabetes.
- All-Korean population.