- Patients with acromegaly have increased risk of developing intracranial meningiomas, according to an observational study.
Why this matters
- The association between acromegaly and meningiomas is poorly understood.
- Patients with acromegaly had increased risk for intracranial meningiomas compared with patients without acromegaly (7.7% vs 2.2%; OR, 3.45; P=.005).
- Patients with acromegaly had increased incidence of intracranial meningiomas compared with the general population (standardized incidence ratio, 126; 95% CI, 25-365).
- 195 patients with acromegaly and 357 patients with nonsomatotropic pituitary adenoma were assessed by gadolinium-enhanced 3D T1 brain MRI for meningiomas.
- Funding: None disclosed.
- Cohorts were not matched for sex, although analysis was adjusted for sex ratio.