A magnetic future for breast cancer localization?

  • Zacharioudakis K & al.
  • Eur J Surg Oncol
  • 26 jun. 2019

  • de Emily Willingham, PhD
  • Univadis Clinical Summaries
El acceso al contenido completo es sólo para profesionales sanitarios registrados. El acceso al contenido completo es sólo para profesionales sanitarios registrados.

Takeaway

  • Magseed localization of nonpalpable breast cancer localization is just as effective as wire-guided approaches for identifying tumors and excising with tumor-free margins.
  • Reoperation rates were also comparable.

Why this matters

  • This alternative allows for continuous reorientation during surgery and decouples radiology and surgery scheduling.

Key results

  • No differences were identified between Magseed and wire-guided localization for:
    • Reexcision: Magseed 16% vs wire-guided 14% (P=.692),
    • Specimen sizes: Magseed 39.6 g vs wire-guided 44.5 g (P=.206); 90.1 cc for Magseed vs 95.6 cc for wire-guided (P=.579), and
    • Successful localization; identification (100% in both groups).
  • 84% with Magseed had 1-mm disease-free margins vs 86% with wire-guided localization (P=.692).
  • 1 patient with Magseed group developed a hematoma that dislodged the seed; a second patient had a skin-adjacent seed dislodged during dissection.

Study design

  • Prospective study, 100 patients having Magseed vs 100 having wire-guided localization, October 2017-September 2018.
  • Funding: None disclosed.

Limitations

  • Surgeons were less experienced working with Magseed.