3 factors predict septic complications after Crohn’s surgery

  • Ghoneima AS & al.
  • Int J Colorectal Dis
  • 8 nov. 2019

  • de Emily Willingham, PhD
  • Clinical Essentials
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Takeaway

  • Preoperative C-reactive protein, hemoglobin, and albumin together predict increased risk for postoperative complications after bowel resection in Crohn’s disease.

Why this matters

  • 1 in 2 patients with Crohn’s disease will need surgery at a decade after the diagnosis, and the complication rate remains high.
  • Factors that predict risk could guide surgical management.

Key results

  • 30% overall had postoperative complications.
  • 13.92% had 2 abnormal values, and 2.53% had 3.
  • This group had a 30.77% rate of postoperative septic-related complications vs 10.6% among those with 1 or no abnormal values (P<.0001>

Study design

  • 79 patients (55 women; median age, 38 [range, 28-49] years) were included, categorized based on number of abnormal values (0-4).
  • Patients were considered to be at high risk with at least 2 abnormal values of the 3 factors.
  • Funding: None disclosed.

Limitations

  • All surgeries were planned.
  • None were for recurrent Crohn’s, which carries a higher complication risk.